The ceramic material overcomes many of the limitations of traditional crystalline hydroxyapatite that prevent its use in industrial scale applications.
Ceramic ha resin.
Hydroxyapatite is the hydroxyl endmember of the complex apatite group the oh ion can be replaced by fluoride chloride or carbonate.
Cht is a mixed mode resin.
These mixed mode resins can be used at any stage in a chromatographic workflow from initial capture to final polishing and are ideal for the purification of monoclonal antibody mab products.
Cht ceramic hydroxyapatite and bio gel crystalline hydroxyapatite resins offer unique selectivities enabling the resolution of mixtures that appear homogenous with other media.
Cht is a leading purification medium of biomolecules.
Cht ceramic hydroxyapatite is a spherical macroporous form of hydroxyapatite.
Ceramic hydroxyapatite cht ceramic hydroxyapatite types i and ii are produced.
Details of the binding mechanism are described in chapter 3.
Cht ceramic hydroxyapatite ca 5 po 4 3 oh 2 support is a leading purification medium for today s demanding downstream process industry.
Its mixed mode support offers unique selectivities and often separates biomolecules that appear homogeneous using other chromatographic methods.
The duration and temperature of the sintering step determine whether the ceramic hydroxyapatite is cht type i or type ii.
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It has been sintered at high temperatures to modify it from a crystalline to a ceramic form.